Design, Synthesis and Biological Activity of Heterocyclic Compounds Containing 4-( Heptyloxy/ octyloxy) phenyl Group 含4-正庚/正辛氧基苯基杂环化合物的设计、合成及生物活性
On the other hand, the percentage of protein displacement increased by 70% due to the introduction of a phenyl group, confirming the enhancement effect of aromatic groups on protein displacement. 同时,Phe-D分子中苯基的引入使模型蛋白的置换百分率提高了70%,展示了苯基对蛋白质置换的促进作用。
Initial and equilibrium octahedral configurations have different additional coordination, the coordination involving phenyl ortho-hydrogen is more stable than that involving terminal hydrogen of R group. The stability of tetrahedronal configuration is lower, the configurational transformation is primarily dependent on the size of R group s. 初始和平衡的八面体构型有不同的附加配位,苯基邻位氢配位比R基端位氢配位更为稳定,四面体构型的稳定性较低,构型转化主要受R基的推动。
It has been shown that the photoelectrochemical properties of tetraphenyl-porphyrin with hydroxyl group on phenyl group was increased and that with methoxy group was decreased. 结果表明,在四苯基卟啉的苯基上的氢被羟基取代后的化合物能增强光电效应。
Compounds derived from phenyl acrylic acid possess anti-anoxia activity if a hydroxyl group is selectively located at m-position of the phenyl ring. 苯丙烯酸类化合物的苯环上m位羟基取代后的化合物有耐缺氧活性。
In the catalyst systems bearing mono ( imino) pyridine ligand, it seems that the substitute attached to the ortho position of phenyl ring has a beneficial influence on the activity while substitute group in the para position has a negative effect. 此外,在含有单亚胺吡啶配体的催化剂体系中,亚胺基苯环上邻位取代基对于催化活性有利,对位取代基则会抑制催化剂活性。
Phenyl Group Eletron Effect Synthesis of Phenyl Cyclohexyl Ketone 苯基电子效应环已基苯基甲基酮的合成
Conclusion Insertion of methylene group between 4-position of phenyl and morpholinyl group in linezolid derivatives can not increase the antibacterial activity. 结论在吗啉恶酮结构中苯环4位和吗啉基之间插入亚甲基,不能提高化合物的抗菌活性。
From the variations of the spectral bands, it is suggested that the scission of the phthalazine ring along N-N bond occurs during pyrolysis, leading to the formation of compounds of phenyl with the conjugated nitrile group and the isocyan group. 根据谱带的变化规律,提出了试样在热解炭化时会沿着二氮杂萘环的NN键断裂,形成共轭腈基及异氰基的苯环化合物。
INVESTIGATION ON NEW ETHYNYL-CAPPED POLYIMIDES Phenyl Group Eletron Effect 乙炔基聚酰亚胺的研究苯基电子效应
In this paper, the synthesis and analgesic activities of some derivatives of 4-methoxycarbonyl fentanyl are reported, in which the 4-N-phenyl group or both the 4-N-phenyl group and the 1-β-phenyl group were replaced by some nonaromatic groups. 一类新型芬太尼衍生物&双芬太尼的合成报道了某些4-N-苯基或4-N-苯基与1-β苯基同时被某些非芳香基团替代的4-甲氧羰基芬太尼衍生物的合成及其镇痛活性。
When it was substituted by other heterocyclic groups, the anesthetic activity decreased. However, some substituted vinyl groups were effective substitutes for 1-β-phenyl group. 结果表明1-β-苯基对麻醉活性起重要作用,被杂环基团取代活性下降,但某些取代乙烯基是可替代该苯基产生强效活性的一个有效结构。
Methods: Using N-phenyl guanidine as a basic structure, a series of guanidine derivatives were obtained by introducing benzothiazole-2-mercapto at the para position of phenyl group, and alkyl, cycloalkyl, aralkyl at the N atom of guanido, and their NOS inhibiting activities were evaluated. 方法:以N-苯基胍为母核,在苯基对位引入苯并噻唑-2-巯基,胍中其他氮上分别引入烷基、环烷基、芳烷基等,并测定这些胍类化合物的NOS抑制活性。
Repulsion between the pinene moiety and a phosphorus phenyl group may result in a conformational change that produces a more crowded active site which may reduced the enantioselectivity of hydrogenation. 配体中哌唏部分与二苯基膦之间的空间上的互斥作用可能引起其构象的变化,反应时产生一个更为拥挤的过渡态,从而降低氢化的立体选择性。
For AAP, the rigidity of the bond between phenyl ring and amino group makes the full elongation of the depth. 对于配体2-氨基-3-(4-氨基-苯基)-丙酸(AAP),苯环和氨基之间的键的刚性使得配体的深度得到完全的增长。
Steady state and time-resolved fluorescence spectra measurement show that the halogen atoms on the meso-phenyl group exhibit significant heavy atom effect on their photophysical property. 稳态和飞秒时间分辨荧光光谱数据显示,这些卤代Corrole的光谱性质表现出明显的重原子效应。
Up to now the studies in this field are mainly focused on those Anionic-nonionic surfactants with fat chain as their hydrophobic group, and investigations of the Anionic-nonionic surfactants having phenyl as hydrophobic group have scarcely been made. 目前在该方面的研究主要集中在疏水基为脂肪链的阴-非离子型表面活性剂,而对于含有苯基结构疏水基的阴-非离子型表面活性剂研究很少。